Posted by Larry Hoover on September 29, 2003, at 11:58:37
In reply to Re: B12 reaction, NADH, nitrates » Larry Hoover, posted by tealady on September 29, 2003, at 0:01:30
> > > BTW , I got some blood tests back this week..no coeliac, (as I expected from an elimination diet years ago. )
> >
> > That would be the anti-gliadin antibody titre?
> Lar below exactly as printed on result form..not a test I'm familiar with
> ----------------
>
> C. Albicans IgA antibodies : negative <10
> Candida IgG antibodies (including C.albicans) : Negative <10
>
> (C.glabrata, C.parapsilosis and C.tropicalis)
> ----------------------That isn't a coeliac test. It's a test for infection by the Candida family of organisms. Sometimes Candida is associated with e.g. leaky gut syndrome, and may be more prevalent in coeliacs (that's also controversial), but it isn't diagnostic for coeliac itself.
The blood test I mentioned is for the antibody to gliaden, a gluten protein. If it has entered the blood, it is presumptive that the mechanism involves intestinal injury from gluten, i.e. coeliac sprue.
> > >
> > > RT3 normal..right in middle of range, which I also kinda suspected and means I can't put my strange reaction to T4 only meds down to that, unless things have changed in the 2 years since I tried T4 only.
> >
> > Are your thyroid symptoms consistent with the blood concentrations? Sometimes I wonder about the possibility of the thyroid version of insulin resistance.
>
> Thyroid hormone resistance is believed to exist I thought..only tested by symptoms, temperature etc though ..don't know a lot about, usually treated (only a few docs WILL treat it)....by high doses of thyroid hormones until non symptomaticThis is one of the issues that is so hard to overcome when dealing with "standard medical practise". Few doctors will treat from symptoms alone. They do a blood test, tell you it's normal (when there is way to much variability in the normal range, in any case), and shrug it off.
I think I need testosterone supps, but I'm going to have a tough time getting it.
> Some folks with this may respond to fish oil??
> Clear the receptors?Fish oil increases receptor sensitivity. Possibly also upregulates receptor synthesis.
> Most female hypos find they are low in ferritin and T3 and ferritin work together, and T3 level influences ferritin level.(Men are usually fine with iron.)Well, there's a lot of weirdness in that too, what with undiagnosed haemochromatosis.
> Been impossible trying to get this up, still not there. Ideal is around 70, should be above 50. ranges wrong..like the B12 tests (I noted iron is involved with the methaemoglobulin stuff too)
Iron malabsorption is charactistic of coeliac, I think.
> B12 and thyroid are linked in there too, some on the PN forum can't get B12 up until took thryoid medsThyroid regulates protein synthesis, and as so much of our biochemistry depends on proteins (enzymes are protein, as are receptors, transporters, and blood-transport molecules), that thyroid defects are really systemic insults.
> Also T3 and acetylcholinerase work together..something I've looked at, with regard to brain function ..unsure of this stuffThe reason fluoride is toxic to thyroid appears to centre around its effects on acetylcholinesterase. The impact is mediated by a host of cofactors, however, but fluorine induces functional zinc deficiency, especially if calcium homestasis is poor, or if iodine deficiency exists. So, given the link of soy and iodine (via genistein), fluorine and soy combined are a thyroid knock-out punch, methinks.
Stuff snipped...
> Thyroid hormone actions and membrane fluidity. Blocking action thyroxine on triiodothyronine effect.
> FEBS Lett. 1977 Dec 1;84(1):199-203. No abstract available.
> [PubMed - indexed for MEDLINE]
> PMID: 145376; UI: 78064714.
> ---------------
> (not sue what this one about- no abstract available)..assuming RT3 from t4 competing with T3?
> ---------------------Well, membrane fluidity is mediated by DHA and EPA (i.e. fish oil), so receptor responsivity seems to have an enhanced response to membrane structure (via an added feedback mechanism). That would be my interpretation.
> I tried going off all meds once last year and onto tyrosine and large supporting supps..I lasted 10 days!before becoming real hypo.Better to think augmentation rather than replacement, methinks.
> If I figure it all out, I'm trying again..but this time very slow taper, not cold turkey...learnt more since then
Reality can be harsh.
> I still have some other problem obviously, and at present need the thyroid hormones to keep me going.
You may always need them. I appreciate that you want to reduce that, to the extent your body will permit it.
> >
> > > I did suspect a small reaction to nitrates years ago in an elimination diet, and I've always limited this..occasionally bacon or corn beef seemed OK though.
> > > It fits in with that dental injection reaction and B12 reaction.
> > > That week I did eat a lot of nitrates so may have built up my level of (lot of leftover corn beef dinner that I froze and too lazy to prepare new food err preferring to spend time on the net?)
>
> Also fits with the oxygen comments I've made, and low ferritin levels.
>
>
> EEG went fine, except she said I was too tense but when she asked me to relax I switched to asleep (no surprise there).You have narcolepsy?
> Apparently people usually don't so this <g>
> ...guess I must have got the idea sometime Definitely was awake for those lights.
>
> JanI'd probably not be nodding off, myself. Frankly, my brain would be trying to steal a glimpse of the data, so I could interpret things myself.....heh. Many times I've made comments to people doing tests on me that just blew them away....they look at me like I'm a freak, like how'd he know that? I used to read The Lancet and the New England Journal of Medicine for pleasure.
Lar
poster:Larry Hoover
thread:259730
URL: http://www.dr-bob.org/babble/alter/20030903/msgs/264225.html