Posted by Larry Hoover on September 21, 2003, at 9:28:44
In reply to Re: NADH methemoglobulin reductase » Larry Hoover, posted by tealady on September 21, 2003, at 7:34:59
> Lar,
> I'm not sure, but if you have missed it, could you please look at this post
> http://www.dr-bob.org/babble/alter/20030903/msgs/261905.html
> I had the wrong title.I've been trying to make sense of the delayed reaction, but it really doesn't make sense to me, unless you have substantial neuropathy. The -caine anaesthetics block sodium channels in nerve membranes. With the channel blocked, the neuron can't fire. If it can't fire, you can't feel.
There's some dependency on the speed of induction of anaesthesia based on tissue pH, but if yours was that awry, I'd be thinking about funeral arrangments.
I can't understand why your reaction would be so delayed. Did this happen once, or is it a pattern?
> This is what I am struggling with at present and where I "got" the idea of NADH methemoglobulin reductase from..and what I really would like some help on..or direction on where to go for help, if possible.
There is always some methemoglobin produced during metabolism of prilocaine. It's a matter of degree, with some people having more than others. If you're deficient in NADH, your recovery period would be prolonged, but it would not be more pronounced than it would otherwise be.
With the collection of symptoms you describe (over multiple posts), you do sound like you might benefit from NADH. Enada is the company that patented the process, but they license the product to numerous vendors. I would presume there is an Aussie vendor.
> It's about my reactions to the dental anesthetic I had on 4th September....
> and then the B12 comes in from studies which is why I bought it up..
>
> I also found old diary notes where I had milder but similar reactions to early B12 needles (in the first month), regarding headaches, anxiety, panic, tingling etc lasting a week.
>
> Thanks, JanThose latter symptoms are suggestive of prostaglandin/cytokine reactions. Hyper-reaction of some sort. You may find that a COX-inhibitor reduces that reaction. That's one of the class that includes aspirin, naproxen, ibuprofen, paracetamol, etc. Or, you could just use tumeric. It has a potent COX inhibitor in it. I prefer it to prescription anti-inflammatories, myself. It's more potent, and lasts longer than anything else I've ever used. I just stir a heaping spoonful into a glass of water, and chug it down. Careful, though, it'll stain anything it touches.
Lar
poster:Larry Hoover
thread:259730
URL: http://www.dr-bob.org/babble/alter/20030903/msgs/262158.html