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Agomelatin: could 5HT(2c) action be bad for sleep?

Posted by psychobot5000 on December 20, 2008, at 19:19:26

So, just to pose a thought--looks like those of us in Europe will soon have Agomelatine as another pharmacalogical tool. Great. One of its benefits is that it may be helpful for sleep, very useful considering how sensitive a bunch depressives and bipolars can be about sleep. But couldn't the increase in frontal cortex activation caused by its serotonin receptor effects (5HT (2c)) disrupt sleep also? Would anyone who knows about this sort of thing care to comment? Is there anything specific that could be done to help with this (other than the usual assortment of sleep drugs like ambien, lunesta and benzodiazepines)?

Psychbot


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poster:psychobot5000 thread:869924
URL: http://www.dr-bob.org/babble/20081214/msgs/869924.html