Posted by Maxime on December 17, 2010, at 20:29:52
In reply to Re: Why do I feel like jumping off a bridge? » Maxime, posted by SLS on December 17, 2010, at 4:48:50
Hi Scott, I find that the trileptal does help with mood swings which is why I am taking it.
Answers below to your med questiosn
> Have you tried the following drugs?
>
> Topiramate(Topamax) ---- Yes, and twice it made me go psychotic. I will not try it again> Clonazepam (Klonopin) ------------ Yes, I was all the way up to 4 mg which is very high and I am now down to .5 mg
> Lithium? Lithium does nothing except make me fat. I have tried it about 4 times and it really does not help me.
> Sertraline (Zoloft) --- This was the last SSRI I took. I was combining it with Wellbutrin and took it on its own. All it did was make me apathetic.
>
>
> - Scott
>
>
> ----------------------------------
>
> Neurology. 2010 Jul 27;75(4):335-40.
> Use of antiepileptic drugs in epilepsy and the risk of self-harm or suicidal behavior.
>
> Andersohn F, Schade R, Willich SN, Garbe E.
>
> Institute for Social Medicine, Epidemiology and Health Economics, Charité-University Medical Center, Berlin, Germany. frank.andersohn@charite.de
>
> Comment in:
>
> * Neurology. 2010 Jul 27;75(4):e12-5.
> * Neurology. 2010 Jul 27;75(4):300-1.
>
> Abstract
>
> BACKGROUND: A recent meta-analysis of randomized trials revealed that antiepileptic drugs (AEDs) as a class increase the risk of suicidal thoughts and behavior. We conducted an observational study with data from the United Kingdom General Practice Research Database to investigate if an increase in risk for different groups of AEDs is also evident in clinical practice.
>
> METHODS: This was a nested case-control study in a cohort of 44,300 patients with epilepsy who were treated with AEDs. Patients with self-harm or suicidal behavior were identified by predefined codes. We included 453 cases and 8,962 age-matched and sex-matched controls. AEDs were classified into 4 groups: barbiturates, conventional AEDs, and newer AEDs with low (lamotrigine, gabapentin, pregabalin, oxcarbazepine) or high (levetiracetam, tiagabine, topiramate, vigabatrin) potential of causing depression. Adjusted odds ratios (OR) were calculated using conditional logistic regression.
>
> RESULTS: Current use of newer AEDs with a high potential of causing depression was associated with a 3-fold increased risk of self-harm/suicidal behavior (OR = 3.08; 95% [CI] 1.22-7.77) as compared with no use of AEDs during the last year. Use of barbiturates (OR = 0.66; 95% CI 0.25-1.73), conventional AEDs (OR = 0.74; 95% CI 0.53-1.03), or low-risk newer AEDs (OR = 0.87; 95% CI 0.47-1.59) was not associated with an increased risk.
>
> CONCLUSIONS: Newer AEDs with a rather high frequency of depressive symptoms in clinical trials may also increase the risk of self-harm or suicidal behavior in clinical practice. For the most commonly used other groups of AEDs, no increase in risk was observed.
>
> PMID: 20660863 [PubMed - indexed for MEDLINE]
Bipolar Type 2, ED-NOS, Self-hatred
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Being happy doesn´t mean the pain is gone. you just bury it deeper.
poster:Maxime
thread:970034
URL: http://www.dr-bob.org/babble/20101203/msgs/973816.html