Posted by linkadge on March 23, 2016, at 17:41:40
In reply to Re: Tricyclics and bipolar depression » linkadge, posted by baseball55 on March 22, 2016, at 19:08:56
The other key problem (that I see) is that all antidepressants essentially work on the same brain systems.
Just because your serotonin, norepinephrine or dopamine are not low, doesn't mean you don't have depression. There are dozens of other mood regulating neurotransmitters, neuromodulators, neuropeptides, hormones etc that can be out of whack. As well there are genes that control intracellular and synaptic connectivity that could effect mood.
We know so little.
If your serotonin isn't low, then it is fully conceivable that artificially boosting it could make you feel worse. How that worse feeling manifests itself, could be very different from person to person.
Linkadge
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thread:1087318
URL: http://www.dr-bob.org/babble/20160306/msgs/1087484.html