Posted by Larry Hoover on June 20, 2003, at 8:39:08
In reply to Re: Methylcobalamin » Larry Hoover » jrbecker, posted by Ron Hill on June 19, 2003, at 19:46:40
> A couple years ago, I started taking 1.0 mg/day of methylcobalamin in a sublingual tablet. I currently take 0.5 mg/day sublingually. The benefit that I experience is noticeable; not profound, but noticeable. YMMV.
>
> Lar, thanks for posting your health concerns regarding cyanocobalamin. I've never read this information prior to your post. Initially, I chose to use the methylcobalamin form of B12 because of its higher bioavailability. Unfortunately, the majority of multi-vitamin supplements contain cyanocobalamin which is problematic if your concerns are valid (and I've rarely seen you wrong).Well, maybe you haven't known me long enough.... ;-)
http://www.strokedoctor.com/vitamin_b12.htm
There's a discussion in this reference that the cyanocobalamin form of B-12 is *not* equivalent in effect to methylcobalamin (the form found in food), at least with respect to the treatment of neuropathies. The references in this paper come from the 70's, while there are a good number of more recent and similar titles in Pubmed, but there are no abstracts available for any of them. (grumble)
Given these concerns, and the simply confusing decision to continue to permit the marketing of a supplement which places a key antioxidant system (glutathione) under additional stress, and which has a bioavailability of something like 1%, baffles my little mind.
Now, I saw methylcobalamin lozenges in the store yesterday, dose 5 mg. Given that the largest dose of cyanocobalamin I came across is 1 mg, and the 1% conversion of the latter to the former, that would make the 5 mg methylcobalamin lozenges 500 times the dose, non? Something still seems weird....
> Do you take a multi-vitamin in addition to your other supplements? If so, what is your favorite brand? Liquid or tablet? I’ve taken a daily multi-vitamin for years and I’ve recently scoured the nutritional store shelves for a good multi that contains chelated minerals and the like. The product that I’m currently using is the best I’ve come across locally, but there are at least two things I don’t like about it. First, it contains 9 mg of iron (as iron amino acid chelate), whereas I would prefer iron-free. Iron-free products are available, but I’ve not yet found a brand that also meets my other criteria. Second, my current multi contains 75 mcg of cyanocobalamin.
I take a multi, but I don't pay much attention to the details, beyond the considerations that the B's are in good concentration (50 or better), and the minerals are chelated. I've never given iron much thought, to tell you the truth.
> For a month or so I took a liquid multi-vitamin. I liked it okay fine, but it’s spendie. I suppose I could bite the bullet and pay the price for a good liquid multi-vitamin and a good liquid multi-mineral. However, the bigger issue is that my wife is already complaining about the amount of refrigerator space I’m taking up with my supplements and a case of Carlson’s fish oil (I buy a case at a time to make it more affordable).You don't need to refrigerate it before it's open. Store in a cool, dark place, but not necessarily refrigerated.
>ut what the heck, what if I just go ahead and put the liquid vitamin/mineral bottles in the fridge? What’s she going to do about it, throw them out? She might threaten to do just that, but she’ll change her mind when I tell her how much they cost.
Don't tell her that.....she'll think you daft.
> -- RonLar
poster:Larry Hoover
thread:234282
URL: http://www.dr-bob.org/babble/20030619/msgs/235365.html