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Re: Morphine for depression. SLS

Posted by Elizabeth on November 30, 2001, at 1:18:38

In reply to Re: Morphine for depression. shelliR, posted by SLS on November 29, 2001, at 17:51:19

> Have you ever tried amantadine (Symmetrel)? It's a long shot, but if Lamictal helped a little, perhaps amantadine could help augment or reduce the induction of tolerance to opioids via NMDA receptor antagonism.

I didn't know that about Lamictal or amantadine. I believe that the current thinking is that NMDA blockers don't really prevent tolerance, they just augment the opioid, alas. I've known a few people who used DXM to that end, although I'm not sure about the effective dose range.

-elizabeth


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poster:Elizabeth thread:84007
URL: http://www.dr-bob.org/babble/20011123/msgs/85593.html