Re: wait, is naltrexone even a kappa antagonist?

Posted by undopaminergic on June 6, 2008, at 8:03:28

In reply to wait, is naltrexone even a kappa antagonist?, posted by iforgotmypassword on June 6, 2008, at 5:05:06

> or is it just a mu antagonist?
>
> have i been under the wrong impression the whole time?
>
It's my understanding that naltrexone is significantly more potent as a mu-antagonist, but that it is also a kappa-antagonist at clinically useful doses. However, I don't have any receptor affinity data at hand.

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