Posted by Britney27 on March 28, 2008, at 21:36:55
In reply to Re: Parnate metabolites, posted by Quintal on March 28, 2008, at 14:48:36
> I had the tightness in my chest and palpitations too so I checked my blood pressure with a cuff I had, and it was still within the normal range. I figured it was safe. It would come on within half an hour of me taking a dose. I also had dilated pupils. I think I was taking it in divided doses of about 30-40mg at a time. A Parnate veteran once told me that single doses greater than 40mg can cause spontaneous hypertensive crises, so I'd be wary of taking too much in one go. In practice I found that the stimulant effect would wear off after a about two or three hours, and I'd usually top myself up when I felt the effect beginning to wear off.
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> I was only on Parnate for a few months when my pdoc pulled the plug and discharged me. Parnate does have 'abuse potential'... i.e. it gets you high given a high enough dose.
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> I remember waking up in the early hours of the morning after maybe three hours of sleep and getting up to walk the dogs and do some work before going to work. Like you, I felt quite energized considering I'd had so little sleep, and I had a very (physically) demanding job at that time too.
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> QWow that describes exactly what happens to me. I have been to the Dr twice when I have had palpitations and chest pain too but my blood pressure turned out to be in the healthy range so I dismissed the symptoms as psychological such as panic attacks which I have never had prior to starting parnate or a symptom that was going to result in me having cardiovascular collapse or cardiac arrest (I am not sure what the difference is between the two). If I do have a spontaneous heart attack or hypertensive crisis I guess this is the risk I am willing to take.
Some research states that pain and palpitations are a "normal" side effect of taking parnate whereas other sources state that you should tell you should immediately tell your doctor if you do experience these. In any case, some sources state that doctors should not rely on blood pressure to see if you are in hypertensive crisis as you could be as a result of hypotension. I just don't understand how sometimes you can have hypotension and sometimes you can have severe hypotension.
I also found the stimulant effect wear off in about 2-3hours and replaced with severe restlessness (I think this is akathsia)and I would have to shake my leg so much that I could actually get up in the morning and go for a run to shake off all the energy. When I am on it, I get 3-4 hours sleep at most but I force myself to try and get 8 hours even though I never fall into REM or deep sleep when I am on it.
To me it feels like I have been to the gym when I have not. Now that I am back at university after my summer break I hope it can do the same the ability to increase concentration levels.
I am not sure if my pupils become dilated as when I shine my lap and look in the mirror they shrink really small.
I am glad that your pdoc pulled the plug on you.Did you tell him you developed a tolerance to it? I get mine from a medical centre with a few GP's and I basically go in and ask for a script and they give it too me no questions asked. I guess in those kinds of practices the main aim is to turn over patients in 5 minutes, thats how they make money.
Britney
poster:Britney27
thread:819514
URL: http://www.dr-bob.org/babble/neuro/20080204/msgs/820412.html