Posted by linkadge on June 13, 2005, at 15:48:51 [reposted on June 14, 2005, at 22:17:35 | original URL]
In reply to Re: Exercise for severe depression » linkadge, posted by SLS on June 13, 2005, at 8:27:16
I would certainly *not* say that exercise does not "work" for the majority of people here.
There are a few posts above of people for whom it does have an effect. And, yes in this devistating illness, (with no magic pill in sight), we must learn to settle for an effect, an improvement.
Think of it this way. My father, who has realized that he no longer needs to get off the couch since the Crestor takes care of is cholesterol quite nicely.Fine, truthfully perhaps, there are people out there whoose cholseterol does not lower sufficiantly with diet and exercise, and for them medication is a must. But I have yet to find a doctor who will give you the go ahead to toss the healthy diet and the exercise. No it may not bring those fast, hardcore digit dropping results that drug companies will kill to achieve.
So what do you think is the cure for depression. Surely you are not still stuck on the second messanger signalling cascade theory. If you are, then you'd better drop the zyrexa, since olanzapine will be sure that your PKC will never see the light of day.
We know that ECT is probably the best antidepressant we have. Show me a study that shows ECT activates second messanger transcripts.
We do know that ECT dramatically increase NT-3, BDNF and NGF. We also know that a single injection of BDNF or NT-3 into the VTA, has a very potent AD effect in animal depression models.
I am very doubtfull that there is a single case where exercise would not offer even the "smallest benefit" over the long term.Linkadge
poster:linkadge
thread:512835
URL: http://www.dr-bob.org/babble/health/20050411/msgs/512850.html