Posted by tealady on September 28, 2004, at 6:41:55
In reply to Re: Supplements for brain fog?- Larry » tealady, posted by raybakes on September 24, 2004, at 13:30:45
> Hi Jan, perhaps it's the noradrenaline that tyrosine is helping synthesize, that is helping with your pain? More from Dr Lowe's website...
>
> "Too little thyroid hormone regulation of other cells in the brain stem decreases the release in the spinal cord of a nerve transmitting substance called "noradrenaline." The decreased noradrenaline in turn reduces the amount of opiates (morphine-like chemicals) released into the spinal cord. These opiates normally reduce the number of sensory impulses that enter the spinal cord and brain stem. When too few of the opiates are released, more sensory impulses make their way into the spinal cord and brain stem. As a result, the patient's perception of pain is heightened.
>
> The combination of high substance P and low noradrenaline (and hence low opiates) causes the patient to perceive pain in the absence of painful stimuli. For example, the patient might perceive as painful the mere movement of some joints. She might experience pain from the pressure on her underside when she is sits or lies on a well-padded surface. And her pain threshold might be so low that she experiences aches and pains despite no apparent stimulus such as movement or pressure."
>
> Ray
>
> http://66.102.9.104/search?q=cache:3-THWVPX1AsJ:www.drlowe.com/QandA/askdrlowe/fmshypot.htm+pain+threshold+noradrenaline&hl=enThanks Ray,
That sounds like one possible explanation. The effect of tyrosine is what I think would be opiate-like(especially when I tried 200mg one morning)..only I haven't tried them.
Maybe I need noradrenaline?I've never heard of this substance P..and
also I have NO idea of the difference between noradrenaline (or norepinephrine ) and adrenaline (or epinephrine ). Every thing I read seems to just mention them mostly together ..or maybe call them different things in different parts of the body. I'm sure they are different though..just confusing for me!
I do know I can't tolerate stress well..like even just a difficult conversation you don't really want to face...eg like some one you employ who is doing a job you don't think is really right..like say my kid's orthodontist. After each visit I'd just crash for a week or so...literally just make it home and collapse into almost a coma (this was before I went onto thyroid meds)..
I'm not sure what exactly was going on with me.
I think it was related to adrenals.
Then later when I went onto thyroid meds I noticed anything that upset me similarly (didn't take much) I'd start shaking violently, vomiting etc before crashing...that's when I realised I had to take cortisol to counteract whatever was happening. I thought maybe adrenaline was going too high and maybe my adrenals couldn't automatically produce the extra cortisol in stressful situations to cope with the increased adrenaline?Anyway tyrosine fits in there ..somewhere! <grin> as it allows me to "cope" with situations a bit better.
Thanks for your thoughts, Jan
PS. I've been researching "thyroid" stuff for about 3 years now(been on thyroid hormones that long)..so I'm kinda mostly "up" on thyroid hormones...but I'm sure lost on adrenals, kidneys, liver etc <grin>.
RT3 is usually raised in nonthyroidal illness...as in hospital patients. The body decides it does not want a lot of normal T3 around for some reason in illness...maybe that forces a person to rest? as their bodies need the rest to recover?
My RT3 was in normal range...but then I never got a T3 to compare it with...can't get one in Oz..only FT3.
My anti TPO are over 2000 in August...ended up taking some cortisol for a few days...it feels like it lowers the antibodies...but it sure isn't something I recommend doing..or want to do too much.
If I don't take the cortisol when my antibodies are raging I partly lose my vision...as well as feel rotten..I can actually feel them in my thyroid..feels a bit like tonsillitis in my thyroid.
At present it's just a scratchy feeling there.
I have been diagnosed with thyroiditis.
Actually, strangely I find penicillin helps too(took a course of that too)..also with my daughters psoriasis..same deal..although I "know" viruses and bacteria are different<grin>I never knew about interleukin..I've heard the name before, but I get lost...seems to be something I need to investigate.
How did you find out about your genetic defect?Nice to "meet" you, been reading some of your posts,
Jan
poster:tealady
thread:359642
URL: http://www.dr-bob.org/babble/alter/20040928/msgs/396166.html