Posted by Skeletor on June 26, 2020, at 16:09:53
In reply to Re: Why does Mirtazapine cause Restless Legs Syndrome?, posted by undopaminergic on June 24, 2020, at 15:34:20
> >
> > BUT opioids induce histamine release, so it could just be a histamine thing?
>
> Some opioids, including morphine, induce the release of histamine from mast cells, which may lead to itching, but (AFAIK) they don't release histamine in the CNS.
>
> -undopaminergic
>Does it need to cross the blood brain barrier or could it stimulate "it" directly in the legs?
poster:Skeletor
thread:1110839
URL: http://www.dr-bob.org/babble/20200511/msgs/1111027.html