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Re: Why does Mirtazapine cause Restless Legs Syndrome?

Posted by undopaminergic on June 24, 2020, at 15:34:20

In reply to Re: Why does Mirtazapine cause Restless Legs Syndrome? linkadge, posted by Skeletor on June 24, 2020, at 8:50:58

> BUT opioids induce histamine release, so it could just be a histamine thing?

Some opioids, including morphine, induce the release of histamine from mast cells, which may lead to itching, but (AFAIK) they don't release histamine in the CNS.





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