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Re: 'safer' not 'better'?

Posted by undopaminergic on May 14, 2020, at 12:11:59

In reply to Re: 'safer' not 'better'? undopaminergic, posted by linkadge on May 14, 2020, at 9:27:00

> >Usually they are called "subunits".
> Pardon my lack of distinction. When I read medical abstracts I'm typically more concerned about the functional relevance and utility of the distinctions rather than specific definitions and classifications.

Of course.

> I am desperate for some nugget of information that might make my life slightly more tolerable, but I rarely care about getting the exact terminology.

I find that I pick up on the terminology pretty easily, although I may not remember it for long.

> I have mainly read about this in reference to the differences in actions of various benzodiazepines or non-benzodiazepine sedatives. For example, some benzos have more anticonvulsant while others may be more amnesic, or sedative etc.

I did a lot of reading on Wikipedia, including the article about the receptor and a multitude of drugs that interact with them. Some were pretty interesting.

> There has always been a 'gaba theory' of depression.

I haven't heard of it. Anyway, that could cut both ways -- too much or too little GABA.

NMDA glutamate receptor antagonists, such as ketamine and memantine, tilt the balance in favour of GABA (and dopamine).





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