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Re: 'safer' not 'better'?

Posted by undopaminergic on May 12, 2020, at 11:59:18

In reply to Re: 'safer' not 'better'? undopaminergic, posted by linkadge on May 12, 2020, at 11:38:55

> The SSRIs can enhance allopregnanolone (which increases GABA-a sensitivity) - perhaps providing mood stabilization.

I think it was the increased agonism at 5-HT2C receptors.

I don't necessarily think it was a mood-"stabilising" effect, rather than just "anti-manic". But at least it's no worse than anti-psychotics.

> When I take (low dose) Effexor, it 'stabilizes' me, but I end up quitting it because I just feel nothing at all.

I have that problem (feeling nothing) but I connect this with depersonalisation, which was aggravated permanently by reboxetine.





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