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Re: What do TRD patients take without an MAIO undopaminergic

Posted by pedr on December 12, 2019, at 14:38:39

In reply to Re: What do TRD patients take without an MAIO, posted by undopaminergic on December 11, 2019, at 9:05:54

> Hello pedr.
> Guanfacine without question, or failing that, clonidine. Possibly prazosin or doxazosin.
>
> You can combine (one of) the former 2 with (one of) the latter 2.

Thanks! I will bring these up with my PDoc. He is very "by the book' however so I don't expect to get anywhere. IIRC we did look at Guanfacine but he didn't like it in the end for some reason.

> > My current rx is (in mg) 40 Fetzima, 30 Lexapro, 30 Ritalin, 60 Adderall, 2.5 Abilify, 45 Buspar, 300 Lyrica, 300 Trazodone, 40 Percocet.
> >
>
> That's quite a cocktail!

:( it's the "best" I've found to date and it's only the stimulants that make me semi-functional.

>
> If you haven't already you may wish to experiment to find the right ratio of Adderall to Ritalin. Ritalin can (dose-dependently, to a degree) inhibit the action of Adderall.

Oo-er, I didn't know that. My mood (and pain and IBS) is so unpredictable, even when on a constant regimen, that I'm afraid I'll never be able to discover the best ratio.

>
> If you have trouble with opioid tolerance, I recommend trying memantine or opioid rotation.

Cool, thanks I'll look into that. Thank you for your help, it's much appreciated.
Pete

>
> -undopaminergic
>


TRD, TR OCD since 1996.
Meds: 40 Fetzima, 30 Lexapro, 30 Ritalin, 60 Adderall, 2.5 Abilify, 45 Buspar (OCD/GAD), 300 Lyrica, 150 Trazodone (sleep), 40 Percocet (Chronic Pain)
Ad hoc: 2 Ativan


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