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Re: What do TRD patients take without an MAIO linkadge

Posted by undopaminergic on December 4, 2019, at 9:19:32

In reply to Re: What do TRD patients take without an MAIO, posted by linkadge on December 2, 2019, at 9:15:25

> I have a bottle of PEA which I use periodically when nothing else works. I prefer it to an MAO-B inhibitor because of half life (much shorter and hence interferes less with sleep).

It's my understanding that PEA without MAO-B inhibition produces no effects, at a dose up to at least 1 gram. At least that's what Shulgin reports. I haven't tried PEA without selegiline, except via phenylalanine (which gets decarboxylated to PEA).

> The problem is that most doctors just throw SSRIs at you and don't really listen to insights gathered through 'experimentation'.

Sadly, that is very true.

> I have issues with attention (either bipolar or ADHD). Interestingly PEA calms me down rather than revs me up. It also clears my head and allows me to concentrate (i.e. read for more than 5-10 min at a time).

That is what amphetamines do in ADHD, often referred to as a "paradoxical calming effect".

I experienced it myself, with the first few doses of PEA.





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