Posted by bleauberry on November 6, 2008, at 18:23:21
In reply to Feeling apathic on Dextroamphetamine - straight up, posted by rjlockhart04-08 on November 3, 2008, at 14:22:33
When it comes to dopamine, I think things are really confusing. I mean, a stimulant at a strong dose should send anybody through the roof, and certainly have nothing at all like apathy attached to it, right? Yet, it can calm hyper kids down. With you it makes you feel zombified and apathetic.
A couple thoughts to ponder:
I've seen at other forums that there is a massive difference between brand Smithklein Beecham and generic, with the generic being absolute garbage in comparison. According to other people, brand amphetamine compared to generic amphetamine is like comparing two totally different drugs, with the generic version being crud. For some people, they gladly pay the higher cost for the quality and uniqueness of the brand version.Reading up on pramipexole I discovered that theories point to the D2 receptors as being responsible for inhibition and anti-anxiety, with the D3 receptors being responsible for the get-up-and-go motivated feelings. Well, in some people they have D3 outnumbering D2 receptors, and in other people it is just the opposite. So if you stimulate dopamine receptors overall in blanket fashion like with a stimulant, and there happens to be more D2 than D3, maybe lethargy and apathy would result? Don't know, just something I was pondering. In the same way, if someone had more D3 than D2, maybe even just a tiny dose would be extremely stimulating?
poster:bleauberry
thread:860566
URL: http://www.dr-bob.org/babble/20081106/msgs/861186.html