Posted by cybercafe on May 24, 2003, at 18:42:22
In reply to Re: abilify/trileptal/zoloft, posted by SLS on May 24, 2003, at 12:14:29
> Hi Mitch.
>
> A partial agonist binds to a receptor just as does an agonist or antagonist. However, it does not always stimulate the receptor into action. I would guess that it probably depends on which of the alternating states (conformations) the molecules exist as they switch back and forth between their different three dimensional arrangements. I'm not sure though.could it be that it stimulates as much as dopamine, but doesn't bind for as long (i.e. less affinity)?
poster:cybercafe
thread:227600
URL: http://www.dr-bob.org/babble/20030520/msgs/228928.html