Posted by SLS on May 24, 2003, at 9:17:32
In reply to Re: abilify/trileptal/zoloft, posted by cybercafe on May 24, 2003, at 2:46:41
me-semantics
>
> hmm... i don't understand why affinity = antagonist
> please explainaffinity: The force attracting atoms to each other and binding them together in a molecule
Affinity is how powerful the "stickiness" is between the ligand molecule (natural neurotransmitter or drug) and the receptor on the surface of the cell. This property is independent of whether the molecule is an agonist, antagonist, or inverse agonist.
Agonist=stimulates receptor to perform a function
Antagonist=blocks receptor to prevent it from performing its function
Inverse agonist=alters the receptor to perform the opposite of its intended function
I hope this helps.
- Scott
poster:SLS
thread:227600
URL: http://www.dr-bob.org/babble/20030520/msgs/228802.html