Posted by JohnX2 on November 8, 2001, at 21:04:54
In reply to Re: DXO vs. DXM (sidetrack) - Cam?, posted by Elizabeth on November 8, 2001, at 19:55:58
Have you been screened to see if you are a
poor metabollizer of cyp450-2d6 (converts the
dxm and many other meds). 5-7% of the caucasion
population has this problem and it could
seriously impact metabolization of many meds
(I don't know off hand if desipramine goes this
route).As far as anti-tussives go, I'll check with
my pharmacist friend and see what he recommends.ps. this is totally offbeat, but I have read
anecdotal experiences on dxm web pages suggesing not
to take Corcidin branch dxm for whatever reason.
Do you have problems with the more standard
Robitussin-DM?Regards,
john
> This thread reminded me of something I'd been meaning to ask about.
>
> I've taken dextromethorphan three times. One of these times, I wasn't taking any other psychoactive meds; one, I was taking Klonopin 1mg tid; and a few days ago, I took it with my current cocktail (desipramine 200mg, buprenorphine 0.9mg, and Trileptal 300mg per day, and Xanax 2mg prn). All three times I took 30mg of dextromethorphan (two times it was in the form of Coricidin HBP, a tablet which also contains 4mg of chlorpheniramine; the other time it was Robitussin Maximum Strength, with no other active ingredients except DXM).
>
> All three times, I got seriously f---ed up a few hours after taking the cough medicine, but I still had a cough! The intoxication lasted for about 36 hours. I've also recently discovered that I appear not to be metabolizing the desipramine properly, in case this is relevant. Any idea what's up? And how I can get rid of my cough??? (Buprenorphine doesn't seem to help either.)
>
> -elizabeth
poster:JohnX2
thread:83228
URL: http://www.dr-bob.org/babble/20011104/msgs/83611.html