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Re: dextrophan vs. dextromethorphan CAM

Posted by JohnX2 on November 4, 2001, at 23:41:51

In reply to dextrophan vs. dextromethorphan CAM, posted by JohnX2 on November 4, 2001, at 23:36:24


my spelling is atrocious.
I hope this doesn't offend anyone.
I say we change the spelling rules
on pbabble. For example, I would like to rename
Adderall Aderal.


>
> Cam et. al,
>
> I found this website with information on memantine.
> It compares the binding affinities of various
> nmda blockers. It acknowledges that the testing
> results were only rough guidlines:
>
> http://www.pano.com/Products/Memantine/body_memantine.html
>
> Also gives a nice little summary of all the various
> little clinical trials.
>
> One thing is interesting in Table1.
>
> Of the low affinity inhibitors (the non-competitive
> and less toxic ones), dextrophan showed substantially
> greater affinity than memantine and then came
> dextromethorphan.
>
> dizcolipine (Mk-801 worst case) > > > > >
> dextrophan > memantine > dextromethorphan.
>
> Due you think this makes dxm less toxic
> if it's plasma ratio dextromethorphan:dextrophan
> was manipulated up. And do you think this would have
> a substantial effect on therapeutic results?
>
> -john


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poster:JohnX2 thread:83228
URL: http://www.dr-bob.org/babble/20011104/msgs/83229.html