Posted by Cam W. on September 24, 2000, at 10:56:44
In reply to Anyone heard of Clomipramine , please!, posted by Lisa Simpson on September 20, 2000, at 8:06:39
Lisa - Clomipramine (Anafranil™) is a tricyclic antidepressant (TCA). All TCAs bind to the serotonin reuptake receptor (like SSRIs, eg Prozac™) and the norepinephrine reuptake receptor (like reboxetine), but their affinities (ability) to bind to these receptors differs. Clomipramine is the TCA that most selectively binds to the serotonin reuptake receptor, very similar to the SSRIs.
In regard to the SSRIs, I guess you could say that clomipramine closely resembles Paxil™ (paroxetine). Clomipramine does cause more sedation (especially for the first 2 or 3 weeks) and can cause heart problems in overdose. Clomipramine works great in OCD and I have seen some success in panic disorder, as well as being a decent antidepressant.
Hope this helps - Cam
poster:Cam W.
thread:44945
URL: http://www.dr-bob.org/babble/20000905/msgs/45187.html