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Re: GABA - natural/synethic?

Posted by JLx on September 2, 2007, at 10:25:52

In reply to Re: Great anxiety product !, posted by linkadge on September 1, 2007, at 13:31:47

Dr. Michael Murray has an article about GABA in his newsletter saying:

"Studies with synthetic GABA have shown that it does not cross the blood-brain barrier very well. That led to the assumption that virtually all of the GABA found in the brain is manufactured there and that supplemental GABA would not increase levels of GABA in the brain. That appears to be the case with synthetic GABA, but not with natural GABA in the form of PharmaGABA - a special form of GABA naturally manufactured from Lactobacillus hilgardii – the bacteria used to ferment vegetables in the preparation of the traditional Korean dish known as kimchi."

He cites a study done in Japan, complete with pic of the anxiety producing bridge. http://www.doctormurray.com/newsletter/05-17-2007.htm

He works for Natural Factors these days, I believe, and PharmaGABA is their product. Is this just marketing or could there be a difference in efficacy between how the GABA is produced? Perhaps this accounts for the conflicting reports.

JL

> The product I took felt like a benzodiazapine on the first dose. YMMV of course, but that was my initial thought.
>
> I have heard a lot of conflicting information regarding GABA. One guy said that the results about GABA not crossing the BBB came out around the same time that gabapentin hit the market.
>
> Who knows.
>
>
>
>
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