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Re: Anyone try CBD?

Posted by undopaminergic on February 20, 2022, at 12:52:57

In reply to Re: Anyone try CBD?, posted by Lamdage22 on February 20, 2022, at 11:42:35

> Anandamide is an endocannabinoid and CBD a phytocannabinoid... Where did you hear that?
>

I don't remember where, but in multiple places. THC is a cannabinoid but CBD is not. By cannabinoid, I mean cannabinoid receptor agonists, and not "constituents of cannabis". I checked Wikipedia, which confirmed that CBD is not an agonist of the usual (CB1 and CB2) cannabinoid receptors, but seems to have a variety of other effects, some of them through pharmacokinetic modulation of THC metabolism, and others pharmacodynamic such as serotonin 5-HT1A partial agonism and allosteric modulation of mu- and delta-opioid receptors.

-undopaminergic


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URL: http://www.dr-bob.org/babble/20220128/msgs/1118684.html