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Re: Atomoxetine: NMDA receptor antagonist

Posted by undopaminergic on July 25, 2020, at 7:11:28

In reply to Re: Atomoxetine: NMDA receptor antagonist rjlockhart37, posted by linkadge on July 24, 2020, at 19:51:26

>
> Some NMDA antagonists display some neurotoxicity i.e. 'angle dust'

Anglo-Saxon dust, to be specific. It was used in battle by the ancient Germanic tribes.

(kidding)

> (Phencyclidine or PCP), ketamine (in high enough doses). However these drugs have many other actions. While many others display no neurotoxicity. NMDA antagonists block the release of glutamate
>

They block the NMDA-subtype of ionotropic glutamate *receptors*. As far as I know, they don't block the release of the neurotransmitter.

> (which generally protects neurons).
>

Can you clarify that? I don't think you mean glutamate protects neurons.

-undopaminergic


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poster:undopaminergic thread:1111340
URL: http://www.dr-bob.org/babble/20200711/msgs/1111368.html