Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Atomoxetine: NMDA receptor antagonist

Posted by undopaminergic on July 25, 2020, at 5:54:37

In reply to Atomoxetine: NMDA receptor antagonist, posted by NKP on July 23, 2020, at 3:16:56

> Apart from its primary effect of being a norepinephrine reuptake inhibitor, atomoxetine is also a mild NMDA receptor antagonist.
>
> To my knowledge, NMDA receptor antagonists are neurotoxic.

It's known as "Olney's lesions". Many NMDA-antagonists can cause it, but there are at least some exceptions, including memantine and xenon. I don't know about nitrous oxide.

> Is atomoxetine neurotoxic, or is it a case of dose maketh poison?

Yes, I'm pretty certain you'd have to take megadoses for this action to be significant. I don't know about the kappa-opioid effect it also has, but personally I would be more concerned about that.

-undopaminergic


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:undopaminergic thread:1111340
URL: http://www.dr-bob.org/babble/20200711/msgs/1111367.html