Posted by undopaminergic on June 20, 2020, at 5:29:46
In reply to Re: Why GABA works, posted by linkadge on June 19, 2020, at 15:04:34
> I've read that GABA can suppress liver tumor cell growth via activation of GABA-A receptors. But you're right. Who knows the implications of flooding the system with a single amino acid.
>
> I definitely notice a muscle relaxant effect of GABA (which can help with anxiety). I don't know if this is due to peripheral effects or central effects.
>
> Linkadge
>Central, I'm pretty sure.
Anticholinergic agents (like atropine or scopolamine) on the other hand work as peripheral muscle relaxants, and can serve as an antidote to poisoning from acetylcholinesterase inhibitors (certain nerve gases and pesticides, and medications eg. galanthamine and donepezil) that induce muscle cramping.
I found your post about hypercholinergia interesting. I've been wondering if I suffer from it too. I recall reading about a "hypercholinergic mouse model of depression", but I must be mistaken, because I can find it now. I think this warrants a thread of its own.
-undopaminergic
poster:undopaminergic
thread:1110736
URL: http://www.dr-bob.org/babble/20200511/msgs/1110872.html