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Re: question: why are MAOIs dangerous with stimulants undopaminergic

Posted by linkadge on May 18, 2020, at 10:37:58

In reply to Re: question: why are MAOIs dangerous with stimulants linkadge, posted by undopaminergic on May 18, 2020, at 8:56:28

I'm not sure. I haven't read too much on the nature of parnate's monoamine release. Unfortunately, I had a spontaneous hypertensive crisis on 40mg of parnate. I was yanked off even though it was working.

>Does that apply to rasagiline?

I would think so. MAO-B inhibitors can greatly magnify the actions of PEA. But you're right, rasagiline doesn't have amphetamine metabolites. Lithium appears to have a push/pull effect on PEA levels (i.e raising it when low and lowering it when high). I've often wondered about the use of selegeline for bipolar depression. I've used PEA + FO-TI before with good results. It is a very fast acting mood elevator. FO-TI contains emodin which is fairly selective to MAO-B inhibiton. I mix the two in a bottle and sip it while I go for a run.




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