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Re: Low-dose buprenorphine (Subutex) for depression

Posted by undopaminergic on April 8, 2020, at 3:25:22

In reply to Low-dose buprenorphine (Subutex) for depression, posted by Hugh on April 7, 2020, at 10:45:09

> Buprenorphine (Subutex) is an opioid that's used to treat pain and, like methadone, is used to get people off of other opioids. Doses vary from 4-24 mg per day. The average daily dose is 16 mg. Much lower doses of buprenorphine, taken sublingually, significantly decreased depression symptoms in people suffering from treatment-resistant depression. Their average daily dose was 0.4 mg.

Buprenorphine (Buprenex, Temgesic, Subutex, Suboxone) is great. In my experience there was a little "half-euphoria" with the first dose or two, but this subsided to the point where there was little or no mood effect. I took it in combination with methylphenidate (Ritalin, Concerta), and that is the best treatment I've ever had for ADHD and working memory.





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