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Re: Nardil to Marplan

Posted by PeterMartin on February 27, 2020, at 21:00:44

In reply to Re: Nardil to Marplan SLS, posted by Jadde on February 27, 2020, at 7:26:55

It's always good to be cautious. Just to offer the other side though, I've gone Marplan to Nardil and back to Marplan cross tapering (1 day washout). I didn't have any problems. There was a study/article from 2018 w a title saying it was ok but sadly the study txt is not free:

J Clin Psychopharmacol. 2018 Feb;38(1):92-94. doi: 10.1097/JCP.0000000000000809.
Monoamine Oxidase Inhibitor Switching Strategies: No Adverse Events Associated With Outpatient Cross-taper or Inpatient Rapid Switch

https://www.ncbi.nlm.nih.gov/pubmed/29189408

Obv it's best to be safe but if you find yourself having to do less than 14days you'll be ok. At least in my opinion.

Btw I'm feeling really good the past few days. It's my 5th or 6th week on Marplan. I had started it while being on Ritalin but I quit taking Ritalin a week ago. I think it was making me worse.

At my pdoc apt on Monday (3days ago) we decided to add a low dose of Desipramine (25mg). Definitely feeling much better w.o. the Ritalin and perhaps the Desipramine is helping my adhedonka a touch already also.

So far so good on this restart of Marplan w. My current cocktail:

Marplan 40
Lamictal 200 (Unichem verified batch by Valisure)
Desipramine 25 (Heritage / ordered verified but seems good)
Metformin 1500 (Mylan)
Seroquel (~15mg for sleep)



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