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Re: Nardil to Marplan

Posted by Jadde on February 28, 2020, at 18:12:24

In reply to Re: Nardil to Marplan, posted by PeterMartin on February 27, 2020, at 21:00:44

> It's always good to be cautious. Just to offer the other side though, I've gone Marplan to Nardil and back to Marplan cross tapering (1 day washout). I didn't have any problems. There was a study/article from 2018 w a title saying it was ok but sadly the study txt is not free:
> J Clin Psychopharmacol. 2018 Feb;38(1):92-94. doi: 10.1097/JCP.0000000000000809.
> Monoamine Oxidase Inhibitor Switching Strategies: No Adverse Events Associated With Outpatient Cross-taper or Inpatient Rapid Switch
> Obv it's best to be safe but if you find yourself having to do less than 14days you'll be ok. At least in my opinion.

Im kinda stuck, I want to be cautious but my pdoc said with the cross taper I would benefit by Marplan working faster coming straight off Nardil. Very tempting. Havent decided yet which way to go. On the bright side, my insurance will cover Marplan. No way I could afford it on my own. I will pick it up tomorrow so I have to make up my mind.

> Btw I'm feeling really good the past few days. It's my 5th or 6th week on Marplan. I had started it while being on Ritalin but I quit taking Ritalin a week ago. I think it was making me worse.

Hey thats great!! My dr wont prescribe most augments other than APs. He mentioned Abilify and Geodon, both of which I have tried and will not try again. Abilify gave me crazy RLS, and Geodon felt like I was in a coma. So Ill stick with Zyprexa or try Seroquel depending on how much trouble sleeping I have on Marplan.

> At my pdoc apt on Monday (3days ago) we decided to add a low dose of Desipramine (25mg). Definitely feeling much better w.o. the Ritalin and perhaps the Desipramine is helping my adhedonka a touch already also.
> So far so good on this restart of Marplan w. My current cocktail:
> Marplan 40
> Lamictal 200 (Unichem verified batch by Valisure)
> Desipramine 25 (Heritage / ordered verified but seems good)
> Metformin 1500 (Mylan)
> Seroquel (~15mg for sleep)
Looks like we may have similar med cocktails. I have Metformin but have been chicken to try it. Does it help with weight gain for you?

Thank you for your post,





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