Posted by Tomatheus on March 20, 2016, at 2:55:28
In reply to Re: Tricyclics and bipolar depression » SLS, posted by B2chica on March 19, 2016, at 15:57:44
> -wellbutrin was the one AD that was amazing, unfortunately it pooped out. i have revisited it twice and still no go.
B2chica,
You might already know this, but data from studies that had been ordered by the U.S. Food and Drug Administration have found that two bupropion products that were previously on the market were not therapeutically equivalent to their brand-name Wellbutrin counterparts. The two bupropion products in question were the 300-mg Budeprion XL tablets (but not the 150-mg Budeprion XL tablets) that were manufactured by Impax Laboratories, Inc., and marketed by Teva Pharmaceuticals USA, Inc., and the 300-mg bupropion HCl ER tablets that were manufactured by Watson. More information regarding the FDA's reviews of various generic bupropion products is available here:
Do you remember if you were taking one of the generic bupropion products that was found to be not therapeutically equivalent to the brand-name Wellbutrin either when the medication seemed to poop out or during the two times when you tried the medication again after that point? Judging from the information in the above link from the FDA's Web site, generic versions of bupropion other than the two that I mentioned in my previous paragraph were found to be therapeutically equivalent to Wellbutrin, but the 300-mg Budeprion XL tablets and the 300-mg bupropion HCl ER tablets made by Watson were not therapeutically equivalent to Wellbutrin. If you took one or both of the generic versions of bupropion that were found to not be therapeutically equivalent to the brand-name version of the medication during the periods when the medication didn't seem to work for you, it might be possible that either the brand-name Wellbutrin or one of the therapeutically equivalent generics could still work for you.
Of course, if you were taking the brand-name version of Wellbutrin or one of the therapeutically equivalent generic versions of the medication when the medication didn't seem to be helping you, then trying Wellbutrin again probably wouldn't make a whole lot of sense, but I just thought that I'd make you aware that two of the generic versions of bupropion that were once available were found to not be therapeutically equivalent to regular brand-name Wellbutrin, just in case you might have been taking one of those versions of the medication that wasn't therapeutically equivalent.
At any rate, I'm pulling for you, and I hope that you'll find something that will work out for you.
Tomatheus
"Maybe someday
We'll figure all this out
We'll put an end to all our doubt
Try to find a way to just feel better now"- Rob Thomas
poster:Tomatheus
thread:1087318
URL: http://www.dr-bob.org/babble/20160306/msgs/1087345.html