Posted by linkadge on March 18, 2016, at 18:40:18
In reply to Re: DHA on methylation, acetylation and neuoprotection » linkadge, posted by SLS on March 17, 2016, at 2:24:56
Hmm. It could be the dose involved with the Zinc that caused the problems. I understand that sufficient zinc is needed for proper brain functioning but elevated levels can be neurotoxic. I don't know if it is related to NMDA hypofunction.
I understand that NMDA antagonists (in higher doses) like ketamine can induce 'dopamine agonist like' neuronal changes and behavioral modifications. Like stimulants, higher doses of NMDA antagonists can mimic a certain forms of schizophrenia and associated brain changes (i.e. decrease in neuroprotective BCL-2 protein). DHA appears very helpful in bipolar / schizophrenia and has many actions in common with mood stabilizers like valproate - especially in mood disorders associated with low BCL-2 and other neuroprotective factors.
Linkadge
poster:linkadge
thread:1087015
URL: http://www.dr-bob.org/babble/20160306/msgs/1087284.html