Posted by linkadge on March 11, 2016, at 21:36:24
In reply to Re: Trying methylfolate, posted by linkadge on March 11, 2016, at 21:32:34
Hypermethylation of the reelin gene can decrease the expression of GAD 67, which presumably lowers levels of gabaergic signalling and possibly inducing mood symptoms in bipolar and/or schizophrenia.
In other words SAMe / deplin might reduce gaba levels over time, relative to monoamines - which could help some depressions but worsen others?
Linkadge
poster:linkadge
thread:1087015
URL: http://www.dr-bob.org/babble/20160306/msgs/1087062.html