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Re: Desipramine Questions

Posted by busub on June 16, 2015, at 13:24:53

In reply to Re: Desipramine Questions » Busub, posted by SLS on June 16, 2015, at 13:03:45

> > Also, would a beta blocker help?
> >
> > Or would it block the effects of desipramine considering its NRI properties.
>
> I don't know for sure. For years, there have been reports of propranolol producing depression as a side effect. However, this is still being debated.
>
> > Would nortriptyline have been gentler?
>
> In most cases, yes.
>
> You might find nortriptyline very tolerable compared to desipramine. If anything, you might experience some somnolence for a few days.
>
>
> - Scott

Thanks for the help Scott.

Another follow up from Pdoc. Gave me the option to split the pill in half and titrate more slowly. Better than nothing I guess, so I'll be taking 12.5mg/night for the time being. I hope that it helps with the uptick in anxiety.

Not considering nortriptyline at the moment as he wants to give the desipramine an adequate trial. Fair enough.

I don't want to poo poo desipramine completely though. I do notice more energy (low energy has been a big problem lately) when the restlessness/anxiety abates for moments at a time. So that's good. I just hope to sustain that as the restlessness ebbs away.


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