Posted by ed_uk2010 on January 9, 2015, at 10:19:35
In reply to Re: Mutiple mechanism with Zyprexa and some atypicals, posted by Lamdage22 on January 9, 2015, at 9:31:24
>But what about TD though??
TD can happen with amisulpride, but it's not as common as with typicals such as haloperidol.
The EPS risk with amisulpride appears rather similar to risperidone.... being highly dependent on dose. The same may apply to TD risk, which is probably higher with risperidone than with olanzapine or (especially) quetiapine. The standard typical haloperidol produces a high incidence of TD at all doses and a very high incidence of EPS except at extremely small doses. I don't think amisulpride is nearly as bad as haloperidol, except perhaps at highly excessive doses. The risk of TD is much higher in the elderly than in young or middle aged adults, it also develops more quickly and is less likely to be reversible.
With amisulpride, those with obsessive-compulsive disorder appear more susceptible to EPS and possibly TD than those with psychotic disorders.
http://www.ncbi.nlm.nih.gov/pubmed/14992963
poster:ed_uk2010
thread:1074889
URL: http://www.dr-bob.org/babble/20150102/msgs/1074997.html