Posted by SLS on December 22, 2012, at 1:16:11
In reply to Re: High fat diet -) inflammation -) depression » SLS, posted by Trotter on December 21, 2012, at 21:18:49
> I don't think it's a coincidence that of the two, EPA is also the only one that reduces inflammation.
I agree with most of what you have to say.
To help bolster your argument, you might want to look into the association between BDNF and inflammation.
It is known that chronic stress is associated with lower BDNF levels, increased cortisol levels, and reductions in hippocampal volume. More recently, inflammation has been observed to be present under these conditions. I would like to see a proposed physiological mechanism that would explain how inflammation may decrease BDNF levels directly, and that this not be mediated through the actions of increased cortisol at the cellular level. It is important to determine the directionality of the associations between cortisol and inflammatory markers. Perhaps the chronic elevation of cortisol produces cortisol-resistance and thereby allows inflammation to occur.
It is possible that you are right about everything. Right now, I am a hard sell.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1033371
URL: http://www.dr-bob.org/babble/20121217/msgs/1033502.html