Posted by CaptainAmerica1967 on October 23, 2011, at 3:39:45
In reply to Re: opiates and major depression, posted by kirbyw on October 22, 2011, at 22:54:27
> I have previously posted that vicodin gives me a lift when I am in a depressive episode. Even a small dose such as half of a 5/500 will give me a big lift for 6-8 hours. The problem is that I don't have a steady supply guaranteed, so I am saving the Vicodin from my last rx, in case of a serious episode. My regular meds are parnate, lithium and 2.5 mg of zyprexa. Since adding zyprexa I have put on 10 pounds, which I don't like at all. I can't determine if the zyprexa is helping or not.
Why don't you ask your physician straight out for Viocodin if it helps? Life is too short to have it wasted on being depression all of your life or at least that's how I feel. If you've had depression all of your life, you'll be on an antidepressant most likely the rest of your life which are also tough in withdrawal themselves. Some individuals the atypical antipsychotics work well, but they make me severely depressed and I've tried all of them for a good lenght of time. I even tried Amisulpride which in low doses is suppose to work as an antidepressant and anxiolytic, but all made me very tired, fatigued, and sleepy, depressed. Lithium I tried many times, but never felt anytime from it really although it's suppose to be a good prophylactic against depression/anxiety and increases brain derived nerve growth factor; I just worried about my kidney because of excessive workout session (sweating and ions) so whenever I tried it I used Lithium Orotate which is much more bioavailable supposedly and therefore can be used on less smaller of a dose, not sure as conflicting reports. It's over the counter.
Maybe print off a study for your physician like the Bodkin 1995 (Havard Study) or Richard Gracer, MD,President of National Alliance of Advocates for Buprenorphine Treatment, NAABT.ORG that wrote an article in March 2007 in the NAABT newletter educationg phyisician on the potential treatment of opioids (smaller doses than addiction) in general but more buprenorphine as it is currently the most potent longest acting kappa antagoinst which he thinks anyone with addiction or depression has a faulty mechanism in general of overactive kappa receptors leading to overactivity of the brain, There's even currently a clinicaltrials.org study for buprenorphine going on called "Buprenorphine For Late-Life Treatment Resistant Depression (BUILD)" where Reckitt Benckiser, Inc., the original developer of liquid buprenorphine who supplied bup. for the Harvard Bodkin 1995 study are supplying the liquid buprenorphine for this study so I wonder if this company, RB, is going to try to market a new form of buprenorphine indicated for treatment resistant depression. Again, liquid bup. given either intranally or squirted underneath the tongue in liquid like the original Bodkin study. Intranasally would be a new form if patented as companies come out with a liquid, chewable, long lasting/extended release or patch forms to hold onto patent to make more money so lets hope RB have plans on marketing bup to TRD patients with indication.
poster:CaptainAmerica1967
thread:81414
URL: http://www.dr-bob.org/babble/20111016/msgs/1000566.html