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Re: opiates and major depression » CaptainAmerica1967

Posted by SLS on October 20, 2011, at 18:47:41

In reply to Re: opiates and major depression, posted by CaptainAmerica1967 on October 20, 2011, at 17:52:15

Nice post.

I don't know if excessive neural activity in Brodman's Area 25 is the root cause of depressive illness or a consequence of it, but DBS works. Outside of this structure, brain activity (FDG uptake) is reduced almost globally as rendered in PET scans. One day soon, we will understand the functions of, and the relationships between, brain circuits.

I am not refuting the idea that overactivity in the subgenual cingulate might be the cause of depressive illness. I just haven't seen evidence that is accepted as being conclusive yet.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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