Posted by Conundrum on December 16, 2010, at 2:36:05
In reply to Re: Looking for some med advice, posted by Hombre on December 16, 2010, at 1:22:36
I had tried Pristiq and found that it seemed to do something, but only for a couple of weeks. So perhaps it would make more sense to start on the prozac and then add remeron or something else, since the prozac won't poop out. Interestingly, energizing effect from desvenlafaxine is what I liked the most. After awhile that went away and so did the "color"
> I only take 150mg effexor xr. I took 75mg by itself a couple of years ago, well, with lorazepam and ambien, and while it did relieve most of my depression symptoms, I still had problems with anxiety, insomnia, and restlessness. But I felt so good that I weaned myself off of all the meds after about 6 months...and subsequently crashed a few months later.
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> I feel good on the combo I'm on, and I think the remeron and the seroquel make effexor much more bearable. Effexor is a bit enthusiastic in terms of raw energy, so having something else to smooth out the edges can change the way it feels. Again, I consider the supplements and regular exercise at least as important as the meds. The meds work with what you've got, and nutrition and exercise improve what you have to work with. Herbs work at an even more fundamental level, but that's another topic.
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> I reviewed the section on combos, and maybe I'm just repeating what you already know, but the addition of atypicals to SSRIs is described as being the best documented example of combining HT2A antagonism with serotonin reuptake inhibition.
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> There also seems to be a lot of different things you could try involving remeron, effexor, atypicals, SSRIs and NRIs. Since this kind of combination strategy is clinically effective for some, but not researched in depth, you can only go so far without actually trying things out. I wouldn't be surprised if wellbutrin felt different with remeron (did you try that? I forget) or an atypical. Who knows, just thinking out loud.It isn't just that wellbutrin didn't work, its that the tinnitus really scared me off it. It was pretty bad. So I wasn't able to tolerate wellbutrin.
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> Since you respond partially to prozac and remeron, it would make sense to build upon one of those. If you don't like effexor after a week or so, I think you could get off of it with minimal discomfort. Short-term discomfort seems to be something we have to get used to during the frustrating trial-stage. It's worth it, IMHO.I think I would be able to tolerate effexor, i'm just thinking it might poop out in a couple weeks like pristiq did. Perhaps I will build upon prozac, since I don't think it will poop out. Ideally I'd like to take a TCA with it, and maybe an atypical. Actually I'd love to add low dose selegiline for some DA, but i think that is not allowed. It is ashame there aren't any pure dopamine reuptake inhibitors with long half lives, I think there is a big difference between the effects of stimulants and drugs that keep levels high constantly.
I know I should exercise, but it just seems so pointless, and I don't even wanna go outside its so nasty out. I'm not working right now, so no gym membership either. I am taking B vitamins now with my SAM-e but that is it.
I used to take a lot for a long time, but they just didn't help. Seemed like a waste of money. I even took a lot of vitamins in liquid forms to increase availability, but I dunno, something is wrong with my brain.
Actually took some remeron tonight, been off it for awhile, but the adderall I'm trialing (and its not working) makes it hard to sleep.
Complaints: post-SSRI problems: anhedonia, memory and concentration problems, sexual dysfunction. )
Country:USA
Currently taking SAM-e 1200mgs
poster:Conundrum
thread:973640
URL: http://www.dr-bob.org/babble/20101203/msgs/973695.html