Posted by medamorphosis on December 17, 2010, at 19:50:33
In reply to Re: Looking for some med advice » medamorphosis, posted by Conundrum on December 17, 2010, at 12:04:40
> I don't know about Marplan, I know that in our family biology, my gmom was treatment resistant and responded to both nardil and parnate, I'm just worried that they will make my memory worse, or the serotonergic effects will be too much to take.
>
> However, I have read about a lot of people saying Nardil really helps with anhedonia. I have not seen the same with Parnate, in fact the opposite more often.
>
> Do MAOI's really cause noradrenaline to decrease, on wikipedia it says they do by displacing norepinephrine with octopime(SP?) but I respond well to increases in NE, so I'm not sure I want a drug that will decrease it.
>
> Decisions, decisions.Never found Nardil nor Marplan make memory worse, quite the opposite. And your brain wont feel sapped with serotonin. Remember, SSRIs 'manipulate' the receptors directly. MAOI dont touch them like an SSRI, simply keeps whats there from becoming zapped by MAO. Norepinephrine? EASY. Use an NRI with your MAOI (bupropion, desipramine are safe. So should reboxetine & Straterra). NRIs have been proven to even help prevent tyramine attacks when used with MAOIs, esp reboxetine, a powerfull NRI! Though when MAOIs kick in they certainly give you drive. DA or NE, Something kicks in and picks you up. And serotonin aint the same feeling as an SSRI, but you'll feel its vast presence. NOT fuzzy but clear, hence why they're so good for social anxiety. Which seems to get worse when you're 'fuzzy'. Just my experiences.
med
U.K.resedent
Ills: AvPD, major depression, addictive personality
Regime: 80mg isocarboxazid, 4mg clonazepam, 25mg Valdoxan, high-dose vit&mins
poster:medamorphosis
thread:973640
URL: http://www.dr-bob.org/babble/20101203/msgs/973810.html