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Agomelatine » SLS

Posted by sigismund on October 20, 2010, at 14:14:32

In reply to Re: Stablon (tianeptine), posted by SLS on October 20, 2010, at 5:29:21

>I have been losing sleep because of the sleep disruptions agomelatine is known to produce early in treatment.

My two bob's worth is that the melatonin agonism is helpful to sleep and the 5ht2c antagonism can be disruptive of it (through the well known dopaminergic effect).

The first time I took 25mg and slept for an hour or two and then was awake for the night.

When I took 12.5mg thereafter my sleep was brilliant (for a while).

 

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