Posted by Elanor Roosevelt on May 31, 2009, at 21:19:19
In reply to Re: When will Agomelatine be available in the US, posted by james_ukglasgow on May 30, 2009, at 2:37:09
Valdoxan resynchronizes circadian rhythms in animal models of circadian rhythm disruption.??? what does that mean?
Valdoxan increases noradrenaline and dopamine release specifically in the frontal cortex and has no influence on the extracellular levels of serotonin.
In humans, Valdoxan has positive phase shifting properties; it induces a phase advance of sleep, body temperature decline and melatonin onset. phase shifting????
poster:Elanor Roosevelt
thread:896778
URL: http://www.dr-bob.org/babble/20090531/msgs/898681.html