Posted by jedi on April 26, 2009, at 1:12:38
In reply to Re: Update on nardil experience, posted by bri on April 20, 2009, at 19:03:14
> I am entering Week 2 of Nardil. After my first 6 days I went up to 30mg from 15mg. I'd been getting GREAT benefits from 15mg (for extreme social phobia and bipolar II depression), and figured 30mg would be perfect. I upped it, and got way anxious again, so now I've bumped it back down to 15mg after spending two days at 30mg.
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> This is Nardil Day 10, very early, I realize. First 6 days: amazing on 15mg. Days 7-8: back to full-on social phobia at 30mg. Now Days 9-10: Back to 15mg/day, and at the baseline social phobia I came into this with.
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> Has anyone had similar experience of doing great with the Nardil very early, and then itcomes back at you full force with horrible phobia and anxiety? I miss those first few days!
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> I'm hoping either, a- 30mg was too much for me and that at 15mg I'll start to see the amazing benefit I first got at 15mg; or b, at 30mg initially the side effects of heightened anxiety was only a temporary side effect and the result of going up too high too soon. I was amazed at how great it was at 15mg and am irrationally worried I took it full-throttle into poop-out mood by going too high. It's been 2 days back on 15mg and it's not as great as it was initially.Hi,
Everyone is different out there but I've never really heard of 15mg of Nardil being enough to induce MAO Inhibition. Like D/R mentioned, you are probably getting some relief from the GABA effect of the med. You probably have a placebo effect going also.To get MAO inhibition close to 90% you will probably need to be at 45mg or more for a period of several weeks. Nardil does not work immediately, but when it does work it is one of those meds that can really make a difference. Sometimes, when it first kicks in, there will be a period of hypomania that is generally short lived. Many people mistake this for the true antidepressant effect of the drug. It is not. I've seen several posters on this board that really craved that feeling and when it went away, thought the med had pooped out. Be careful of that. For the right person, Nardil can be a true miracle. It will often work where many other medications have failed.
Good Luck,
Jedi
poster:jedi
thread:887994
URL: http://www.dr-bob.org/babble/20090416/msgs/892820.html