Posted by desolationrower on December 1, 2008, at 13:57:03
In reply to Re: Need advice! Nardil switch to Parnate!! » desolationrower, posted by JadeKelly on November 28, 2008, at 20:08:05
> > The initial anxiety of ssris is probably about serotonin2 receptors, you might want to try adding an antagonist to your current meds.
> >
> > -d/r
>
> Thanks d/r, any meds come to mind? What your saying is that if I don't need seratonin, a blocker could take that (or the anxiety part) out of the mix? I did once try Prozac for 30 days. I was anxiety ridden the entire time. I was so happy to be off it I went into remission (NOT).
>
> ~Jade
>
>ack forgot about this. There are lots of 5ht2 antagonists, and none of them are perfect (have other effects too). Include low dose of most atypical antipsychotics, especially risperidone, which is probably the most practical, although some risk if you are a slow metabolizer of it; if you get big pills and spit them its not that expensive. Nefazadone, but its hard to get because of the liver problem. mirtazapine, but only once the other effects kick in too, so not a good choice, though part of why it is a good combination with sris. A number of the TCAs, i think doxepin & amytryptiline being the most potent, but these are stronger antihistamines, so they and also 5ht2 anagaonist cyproheptadine, they could be taken before bed as low dose to improve sleep, and might help with anxiety the next day to some extent. pizotifen, i think its hard to get, and docs will be confused. ketanserin, i don't nkow if you can get this, its used sometimes in studies of the receptor. Might be some othesr i'm forgetting.
-d/r
poster:desolationrower
thread:863385
URL: http://www.dr-bob.org/babble/20081123/msgs/866088.html