Posted by JadeKelly on November 29, 2008, at 0:30:36
In reply to Re: Need advice! Nardil switch to Parnate!! » JadeKelly, posted by Nardilstarted 2007 on November 28, 2008, at 22:33:07
> Bonjour, So you feel the NE/Epinephrin kick as soon as you took 40mg... thats good to know because I can assume its working quite similar for you as it does for me. I expect that good feeling you get will dissapear any day now and you'll feel like its doing nothing
(except the side effect like heart racing at dose time, insomnia, maybe jittery.. at least those were some for me)Well aren't you just a pocket full of sunshine!.
I say I take a high dose (60mg/day) because thats the highest dose approved by the FDA and 30mg/day is recomended starting dose. SOme peole on Parnate take up to 200mg/day which blows me away! I guess that shows how desensitized some peoples brains get to these meds. If you stick at 40mg/day for another 2.5 weeks you should know if its working or not. If not, try 50 mgs for another 3 weeks (im sure youll get those initial good feelings as soon as you increasy your dose but will go away. then you gotta wait the whole 3 weeks to see if the "real antidepressant effect" will kick in.
> WHen I started at 50 mgs I went MANIC, very hyper very happy, so I dropped to 40 like I mentioned before. WHat happened was that it was those initial good feelings, not the real antidepressant effect that were too strong. The next shot at 50mgs after 3 weeks at 40mgs I could tolerate the good feelings for the first 3 days without going too manic. Then 3 weeks later, nothing. Once I hit 60 mgs I had the initial good feelings which went away after 2 days but the Real Antidepressant Effect kicked in after about 10 days at 60 mgs. ( I know I repeated alot of the same stuff ive said before, I guess im just making sure i was right in the first message)
> As for weight it doest matter too too much like it does with Nardil. Nardil you can expect it to work at 1mg/kg of body weight. it Varies signifigantly for some people tho. if your 125lbs Id suspect 30 - 50mg's will work but youve already prooved 30 mgs does not. Just a note: it can take 6 weeks at each dose increase to know foresure that it will, or will not work. It just "usually" works within 2-3 weeks after youve been on a lower dose for 6 weeks. IM not gonna wait 6 weeks at every dose increase if it usually works after 3 when titrating up dosages. I have severe social Anxiety disorder which leads to depression and agoraphobia. Depression SUcks Dong and Anxiety ontop is a killer. ANd O mighty Parnate, The Last drug I have tried. This is almost my last resort. After this it will be on to Weird off label Pharmaceutical mixtures of my own making ahha. I Know Parnate isProbably The #1 best Antidepressant in the world. its not very good for Anxiety but thats for most people. it seems to be doing a great job on both. AND YES my days are split feeling. Morning I feel so sensitive I could cry at anything. Its not that bad I just have very over stimulated feelings. by afternoon i just like the antidepressant effect and anti anxiety.. Next Post Ill write a list of drugs that worked and did not and their issues. Hope this helps I love talking about it. Feel free to tell me lots more , I just gotta go here at the moment..Wait...its the weekend and your saying you have something better to do than talk to me? Well, frankly Phil, I'm hurt. So, I thought you were done titrating at 60mg. Do you expect to go higher? As for sensitivity and crying, and overstimulated feelings, bring it on. I've been numb for far too long. Time to face the music (I'm afraid to face the music).
Sorry your depression "sucks dong" and your anxiety is killer. A bad combo. But you are still in remission tho, right? I didn't know you had anxiety for some reason. Did you have agoraphobia before, or did it come as a package deal with depression? Just rechecking our similarities. Mine is loss of most previous pleasures. I still like to breathe. I literally feel numb and lethargic. My emotions (or lack thereof) would be the most striking symptom. Total shut down, although I do feel agoraphobic and have anxiety if around other people at times. Never had either of those. Still sound familiar?
So, other meds list can wait, I don't plan on going off Parnate any time soon, but I would like a back-up plan just in case. Little nervous about going up to 50mg but I will if thats what it takes.
OK, you take care of business and I will chat with you next time!
~Jade
PS-3 days of feeling normal to good, eves, not so much. May be wearing off. One step closer.....
poster:JadeKelly
thread:863385
URL: http://www.dr-bob.org/babble/20081123/msgs/865681.html