Posted by Vincent_QC on November 30, 2008, at 4:18:42
In reply to Re: no stims/no benz BEST NARDIL AUGMENTION d/r, posted by desolationrower on November 30, 2008, at 1:39:06
> I don't think an MAOi switch should take more than a day or two, but some pdocs really fear MAOIs and are cautious. They have very short half lives, couple hours. Why would you let MAO regenerate, just to inhibit it again? The only thing i could think of would be the other amine oxidase enzymes that these drugs may inhibit might do something? I switched from deprenyl to parnate, just stopped taking the deprenyl one morning and took parnate instead.
>
> -d/r
That's what I think also. No danger cause they can only destroy type A or B enzymes...since Parnate have a really short half-life (5 hours max), it seem to destroy more the type B enzymes, and Nardil have a 12 hours half-life and destroy the same amount of the Type A and B enzymes + act on the gaba receptors, that's the only difference...but the effect of Nardil on the destruction of the enzymes seem to last a couple of weeks but not for the Parnate...so what is the difference, switching from one to another, it can't be fatal! You don't need a washout period. I switch from Parnate to Nardil after 1 day without any problem at all...If the Nardil fail to show some positive relief effects of my social phobia and anxiety after 3 months , I will switch to Manerix (Moclobemide) without a whasout period also...I know it's not as powerfull than Nardil or Parnate, but it's the only one I never try...
My pdoc told me to wait a couple of days before switching from Parnate to Nardil...but I don't listen to him. He seem to fear the MAOI a little bit...but at the same time he said that he is open minded on that question...??? I think he is not so open minded...since he don't want to prescribe at the same time a little dose of Trazodone for my insomnia...but for god seek, I need it!!! lol I don't sleep more than 2 hours in a row since 1 week or so...and I begin to feel really tired...
poster:Vincent_QC
thread:863270
URL: http://www.dr-bob.org/babble/20081123/msgs/865863.html