Posted by bleauberry on May 7, 2008, at 17:35:36
In reply to Fast acting options for suicidal ideation?, posted by Racer on May 6, 2008, at 10:00:21
Hi Racer, I hope today is a little better than yesterday. I had some thoughts on your situation today.
One thing that might help is to reduce the doses of meds, probably wellbutrin first. Really. I know that sounds weird. You know yourself that when something isn't working and you stop it you actually feel a little better almost right away. I'm not saying stop any drug, just cut back on dosage. I know that sounds weird but I am serious.
Too much dopamine and/or norepinephrine stuff will make a majority of people very depressed. For example, one of the common consequences of high dose stimulants for some time period is either psychosis or depression. You would by no means be the first person that got depressed on wellbutrin, even after it had once worked very well in the past. You would by no means be the first person that got depressed at too high of a dose of wellbutrin. The other meds are also pumping up dopamine and norepinephrine and that can lead to a very dysphoric depressed lethargic feeling, way beyond the window of feeling energy and joy from dopamine enhancement.
Didn't you recently stop a lengthy failed trial of Ensam? If that was you, well, there again is a clue that the dopamine/norepinephrine accumulation thing is not what your brain needs at this point in history. Maybe you would do better with things that stimulate the release of neurotransmitters versus damming them up at the synapse.
Someone else mentioned Memantine and while that post could easily be missed or quickly forgotten, I think there is a ton of potential in that one. If you once did well on the dopamine/norepinephrine stuff but now you aren't, Memantine is known to restore those good effects. There have been a couple spectacular examples at this site and I've seen them at other forums also. I mention it because everyone who responded to it did so within about a week.
poster:bleauberry
thread:827471
URL: http://www.dr-bob.org/babble/20080430/msgs/827807.html