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Re: Fast acting options for suicidal ideation?

Posted by undopaminergic on May 7, 2008, at 15:10:37

In reply to Fast acting options for suicidal ideation?, posted by Racer on May 6, 2008, at 10:00:21

Sulpiride (and probably amisulpride) has a rapid onset of action - within hours in my experience.

Selegiline also act rapidly, whether due to the elevation of phenylethylamine (PEA) or the amphetamine metabolites. Augmentation with phenylalanine or PEA is possible if selegiline monotherapy proves insufficient.

Dextroamphetamine (Dexedrine) and other amphetamines definitely have a rapid onset of effects. However, tolerance often devlops rapidly, and many users notice a "crash".

Pramipexole (and probably ropinirole) produces noticeable effects within hours, although nausea may be a troublesome adverse effect.

Reboxetine produced definite effects within a couple of days for me, and its reduction of negative and self-critical thinking has lasted to this day (many years after quitting it).

Lithium and memantine are options worthy of consideration.


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